Hip Hop Is Dead
 
Nas performing in Ottawa, 2007.
In January 2006, Nas signed a label deal with Def Jam, emphasizing collaboration over competition with former rival Jay-Z.[5] Nas original title for his next album was Hip Hop Is Dead...The N[21] (shortened to Hip Hop Is Dead), though the UK release features a bonus track at the end called "The N." The album featured production from will.i.am, Kanye West, Dr. Dre, Scott Storch, and NBA All Star Chris Webber, as well as longtime Nas collaborators L.E.S. and Salaam Remi. A street single named "Where Y'all At" was released in June 2006. It was produced by Salaam Remi[22], and contained a sample from Nas "Made You Look,"[23] but it did not make the final cut for Hip Hop Is Dead.[24]

The title record and first single was produced by will.i.am, and contains the same melodic sample ("In-A-Gadda-Da-Vida") as Nas' 2004 single "Thief's Theme." The album debuted on Def Jam and Nas new imprint at that label, The Jones Experience, at number one on the Billboard 200 charts, selling 355,000 copies—Nas's third number one album, along with It Was Written and I Am….[25] A music video for "Can't Forget About You" premiered on February 5, 2007, the song featuring Chrisette Michele and sampling Nat King Cole's song "Unforgettable". [26] Another video, Hustlers, featuring The Game, would follow. [27] Also, Nas has stated in an interview with MTV that a video for "Black Republican" featuring Jay-Z is also underway. A reality series on MTV entitled Me and Mrs. Jones will feature the lives of Nas and Kelis, with Vibe magazine has reported that the show will premiere in 2008.[28]

The title of the album generated controversy, as many fans and artists (particularly those of Southern origin) began to debate over the actual state of rap music's vitality. With this album Nas became an unofficial leader of the "Hip Hop Is Dead" movement. Ghostface Killah, on his album Fishscale seemed to agree with Nas and cited Southern crunk and snap music as the primary reasons for why hip-hop was "dead". Many Southern acts, such as rappers Big Boi from Outkast, Lil Boosie, T.I., Young Jeezy, Dem Franchize Boyz, and D4L took offense to the title, taking it to be directed at their region in particular.[29]. Though southern rapper Andre 3000 from Outkast said in a interview that hip-hop is "dying".

Nas worked on a song called "Shine On 'Em" for the film Blood Diamond starring Leonardo DiCaprio and Djimon Hounsou, which opened in US theaters on December 8, 2006. His song "Thief's Theme" was featured in one of the scenes in the Academy Award-winning movie The Departed directed by Martin Scorsese.[30]